Learn what "you cheated on me with my best friend" means, when people say it, and how to use it naturally in English.

This is a direct accusation that someone was unfaithful and betrayed you.
From Tied By Fate, Episode 33
She accuses someone of cheating with her best friend.
Use it in a serious argument or breakup scene. It sounds very painful and confrontational, so it is not polite or light conversation.
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