Learn what "it's the last loose end finally tied up" means, when people say it, and how to use it naturally in English.

It means the final unfinished problem has been settled.
From Help! I’m Falling In Love With My Rude CEO, Episode 52
Someone says the final unresolved problem has finally been settled.
Use this in work or personal situations when the final detail is finished and things are complete. It sounds natural in speech and writing, especially for closures or wrap-ups.
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